Увеличивает выработку инсулина, но только когда сахар высокий (глюкозозависимый эффект, поэтому риск слишком гипогликемииминимален)
Снижает уровень глюкагона — гормона, который повышает сахар в крови
Tirzepatide: A Modern Medication Against Diabetes and Excess Weight
How it helps reduce weight:
Reduces hunger by affecting appetite centers in the brain. Mediates control of eating behavior
Slows stomach emptying, so the feeling of fullness lasts longer
Increases insulin sensitivity in adipose and muscle tissues
Enhances glucose uptake by muscles
Strengthens lipolysis
Increases calorie expenditure by enhancing thermogenesis
Additional benefits:
Reduces the likelihood of cardiovascular complications
Tirzepatide is a new peptide medication for the treatment of type 2 diabetes and excess body weight. Its special feature is that it activates two important hormones (GIP and GLP-1) that regulate metabolism. It represents an advanced peptide molecule designed for comprehensive therapy.
Unlike semaglutide and other medications that primarily affect GLP-1 receptors, tirzepatide is a dual agonist of GIP + GLP-1 receptors, which provides higher efficiency in key parameters: pronounced body weight reduction and control of blood sugar and glycated hemoglobin levels. Clinical studies confirm the superiority of tirzepatide over semaglutide: weight loss with tirzepatide can reach 20-25% of the initial weight, while semaglutide provides weight loss of approximately 15%
How it's better than other similar medications:
Makes cells more sensitive to insulin, reducing insulin resistance
Enhances glucose uptake by cells
Reduces the level of glucagon – a hormone that raises blood sugar
Increases insulin production, but only when blood sugar is high (glucose-dependent effect, so the risk of hypoglycemia is minimal)
Improves the function of pancreatic beta cells
How it helps control blood sugar:
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4 µg of lyophilized plasmid containing your gene insert
Sequence chromatogram covering your gene
Map of the final plasmid vector
Certificate of quality
Additional Options
Specialist assistance in construct design
Cloning of the insert into an expression vector
Free optimization of the gene sequence
Gene synthesis from 150 to 8000 base pairs
The cost of synthesis is calculated individually based on the GC content of the sequence, presence of repeats, complex structural elements (such as hairpins), and complex regulatory elements
We produce recombinant proteins in E.coli. We lead projects from design of amino acid sequence of protein and synthesis of genes to development of experimental and industrial regulations of recombinant protein substance production of pharmacopoeial quality