SOMATOMEDIN

Main research area
Tissue regeneration, activation of muscle growth, neurogenesis, neuroprotection, geroprotection
CAS No.
61 912−98−9
purity
over 97%
Storage
up to +4−8 °С
Molecular weight
7654.74
Amino acid sequence
Gly-Pro-Glu-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val-Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala
* Product samples presented on our website are for research purposes only

Insulin-like Growth Factor-1 (IGF-1): An Important Regulator of Growth and Recovery. IGF-1 is a protein similar in structure to insulin. It plays an important role in regulating the growth, development, and renewal of cells and tissues in the body. IGF-1 is the main mediator of growth hormone (somatotropin) action and provides most of its beneficial effects in tissues. In addition, IGF-1 enhances the body's protective properties, reduces oxidative stress and inflammation, slows the development of atherosclerosis, helps restore blood vessels, and promotes the formation of new blood vessels. In the nervous system, IGF-1 promotes axon growth and myelination, has a neuroprotective effect, and prevents age-related decline in cognitive abilities.

The main functions of IGF-1 include:
Strengthening bones, increasing density, reducing bone tissue resorption
Improving amino acid delivery to cells and stimulating protein synthesis in cells, which helps build muscle mass and strength
Reducing inflammation and oxidative stress in the body
Increasing cell sensitivity to insulin
Regulating blood sugar levels
Supporting the growth and restoration of blood vessels
Accelerating skin cell renewal, smoothing wrinkles, and increasing skin elasticity
Increasing resistance to stress
Supporting kidney function
Enhancing lipolysis
Improving the function of nerve and immune cells
Supporting heart function
Increasing sexual activity and fertility

The use of IGF-1 helps maintain normal weight, activates brain function, improves sleep, increases physical strength, and enhances sexual function.

Furthermore, IGF-1 reduces blood sugar and insulin levels, making it an important component in combating age-related decreases in insulin sensitivity and related aging processes. Research shows that IGF-1 improves the condition of patients with cardiovascular diseases.
When applied topically, IGF-1 provides the following effects:
Antioxidant and restorative action
Improved hair growth
Anti-aging effect, improved collagen and elastin production
Reduction of wrinkles and prevention of new ones
Regulation of sebaceous gland function and anti-inflammatory action
Help in fighting skin problems (acne, pimples)

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Dublin, Ireland
RU
ALL PRODUCTS PRESENTED ON THIS WEBSITE ARE INTENDED FOR RESEARCH PURPOSES ONLY. They are designed for in vitro testing and are strictly for use in laboratory experiments. All information provided on this website is for educational purposes only. Any administration of these products to humans or animals is strictly prohibited. It is essential that these products are handled only by licensed and qualified professionals. These products are not intended for use as drugs, food, or cosmetic products. They must not be mislabelled, misused, or misrepresented as such. Their intended purpose and use are strictly limited to scientific research.
Molecular Design of Recombinant Products
[01]
Development of target protein or DNA sequences, insert, and vector design using in silico methods as part of R&D activities
[02]
Production of recombinant proteins
Bacterial expression
Eukaryotic expression
Development of purification methods for recombinant proteins as part of R&D activities
[03]
Molecular Biology Services
Gene synthesis
Cloning of sequences into vectors
[03]
Plasmid DNA Production
Bacterial expression
Development of purification methods for plasmid DNA as part of R&D activities
[05]
Peptide Synthesis
Gene Synthesis and Cloning of Genetic Constructs
Our Capabilities
4 µg of lyophilized plasmid containing your gene insert
Sequence chromatogram covering your gene
Map of the final plasmid vector
Certificate of quality
Additional Options
Specialist assistance in construct design
Cloning of the insert into an expression vector
Free optimization of the gene sequence
Gene synthesis from 150 to 8000 base pairs
The cost of synthesis is calculated individually based on the GC content of the sequence, presence of repeats, complex structural elements (such as hairpins), and complex regulatory elements
Development of production strains
Term from 4 weeks
Free Gene Optimization
Service of guaranteed protein production
We produce recombinant proteins in E.coli.
We lead projects from design of amino acid sequence of protein and synthesis of genes to development of experimental and industrial regulations of recombinant protein substance production of pharmacopoeial quality
Analytics
Verification of Sample Authenticity and Purity
N-terminal sequencing
Chromatography
Spectrometry
Quantitative analysis
HPLC, MS, NMR, GC
Accelerated aging
Stability testing
Preparation of Analytical Report
Purification
Preparative purification of recombinant proteins and DNA
Preparative reversed-phase, normal-phase, hydrophobic, and ion-exchange chromatography
Purity level up to 99%
Technology
Development of preparative purification technology for recombinant proteins and DNA
Drafting laboratory and industrial protocols
Technological process flowchart
Description of the technological process by stages. Material balance. Equipment requirements
Cost calculation
Scaling of the technological process
Consultation
Providing consulting services as part of R&D
Study of patent, scientific, and technological literature
Literature and patent search
Preclinical and clinical studies, conditions, and results
Development of formulations for dietary supplements and cosmetics
CONTACT US
By clicking the "Submit" button, you agree to the Privacy Policy
Fill out the feedback form and we will get back to you within the day